10 Famous Nurses Who Shaped the World of Nursing

Last Updated/Verified: May 14, 2025

Nursing is the backbone of healthcare systems around the world. According to the World Health Organization, nurses and midwives make up nearly 50% of the global health workforce. With such a critical role in patient outcomes, policy advocacy, and health innovation, it’s no surprise that nursing has produced some of history's most influential figures.

From wartime heroism to groundbreaking public health campaigns, famous nurses have shaped how we practice, teach, and think about nursing today. Their stories offer powerful lessons in resilience, leadership, and patient advocacy—qualities that are especially relevant to today's nurse practitioners and aspiring clinicians.

This article honors 10 exceptional nurses whose legacies continue to impact the nursing profession. Whether you are just beginning your path in healthcare or are advancing into leadership, these individuals offer inspiration and guidance for forging your own legacy in nursing.

Nurses Who Changed the Course of Healthcare

Below is a closer look at 10 trailblazing nurses who made history through compassion, innovation, and tenacity. Each profile highlights their background, contributions, and the enduring significance of their work in modern nursing.

Florence Nightingale (1820–1910)

Florence Nightingale is considered the founder of modern nursing. She gained worldwide recognition during the Crimean War for her work improving sanitary conditions in military hospitals, reducing death rates dramatically.

Impact: She established the Nightingale School of Nursing and authored Notes on Nursing, which is still referenced in nursing curricula today. Her legacy influences infection control taught in online BSN-to-NP programs.

Clara Barton (1821–1912)

Clara Barton served tirelessly as a battlefield nurse during the American Civil War and later founded the American Red Cross, setting a precedent for organized emergency response.

Impact: Her legacy lives on in disaster relief protocols and humanitarian work performed by Red Cross organizations globally, shaping how acute care nurse practitioners prepare for emergency scenarios.

Mary Eliza Mahoney (1845–1926)

Mary Eliza Mahoney was the first Black woman to graduate from an American nursing program and become a licensed nurse in the U.S., as recognized by the American Nurses Association.

Impact: She co-founded the National Association of Colored Graduate Nurses, breaking racial barriers and advocating for professional equity—a movement that supports diversity in MSN programs for nurse practitioners.

Margaret Sanger (1879–1966)

Originally trained as a nurse, Margaret Sanger championed women's access to birth control and reproductive education, founding organizations that evolved into Planned Parenthood.

Impact: Sanger’s advocacy paved the way for modern reproductive health services and family planning education, areas of care frequently addressed in FNP curriculum tracks.

Virginia Henderson (1897–1996)

Virginia Henderson developed the "Need Theory," defining the nurse's role as helping patients gain independence as quickly as possible (National Institutes of Health).

Impact: Her model is taught in nursing schools around the world and remains a cornerstone of patient-centered care. It is echoed in DNP programs that emphasize leadership and holistic approaches.

Mabel Keaton Staupers (1890–1989)

Staupers advocated for the full inclusion of Black nurses in the military and the broader profession during and after World War II.

Impact: Her work helped desegregate the Army Nurse Corps and the American Nurses Association, contributing to the inclusive environments seen in today's online nurse practitioner programs.

Dorothea Dix (1802–1887)

Dorothea Dix was a social reformer who campaigned for humane treatment of individuals with mental illness. She served as Superintendent of Army Nurses during the Civil War.

Impact: Her advocacy led to the creation of the first mental health institutions in the U.S. Her influence is present in the scope of practice for psychiatric nurse practitioners featured in NP specialties.

Edith Cavell (1865–1915)

A British nurse during World War I, Cavell was executed for helping Allied soldiers escape from German-occupied Belgium (National WWI Museum and Memorial).

Impact: Her commitment to duty, even in the face of death, has made her a symbol of nursing ethics and bravery—qualities emphasized in advanced clinical training.

Hazel W. Johnson-Brown (1927–2011)

Johnson-Brown became the first Black woman to lead the U.S. Army Nurse Corps and to be promoted to brigadier general.

Impact: She opened doors for minority nurses in military leadership and promoted education and equity, paving the way for more diversity in leadership-focused NP programs.

Linda Richards (1841–1928)

America's first professionally trained nurse, Richards helped standardize nurse training programs in the U.S. and introduced record-keeping systems still used today.

Impact: Her emphasis on clinical education and documentation raised the standard of care and professionalism in nursing, forming a foundation for today's NP education pathways.

At-a-Glance: 10 Nurses Who Shaped Nursing History

NameKnown ForLasting Impact
Florence NightingaleSanitation reforms, war nursingFounded modern nursing and nursing education
Clara BartonCivil War nurse, American Red Cross founderModern emergency response systems
Mary Eliza MahoneyFirst Black licensed nurse in U.S.Advocated racial equality in nursing
Margaret SangerBirth control and reproductive health advocateReproductive health access and education
Virginia HendersonNursing theory and educationGlobal influence on nursing curricula
Mabel Keaton StaupersNursing desegregation activistIntegration of Black nurses in the military
Dorothea DixMental health care reformEstablishment of mental health institutions
Edith CavellWartime resistance and humanitarian aidNursing ethics and moral courage
Hazel W. Johnson-BrownMilitary nursing leadershipPromoted diversity and education in military nursing
Linda RichardsFirst trained nurse in the U.S.Standardized nursing education and documentation practices

How These Nurses Inspire Today's Professionals

Learning about these trailblazers can deeply inspire nurse practitioners and students pursuing the field. For example, Florence Nightingale’s focus on sanitation resonates in today's infection control practices, while Virginia Henderson's nursing model still guides clinical care plans.

Nurses like Mary Eliza Mahoney and Hazel Johnson-Brown laid the groundwork for inclusive practices that shape modern diversity initiatives. Their stories remind healthcare professionals that nursing is not only about clinical skills but also about leadership, advocacy, and innovation.

Taking the Next Step in Your Nursing Journey

As you chart your path in nursing—whether through clinical practice, policy, education, or entrepreneurship—consider the courage and dedication these figures brought to their work. Their achievements show that with the right preparation and mindset, nurses can influence not just individual lives but entire systems of care.

Explore online nurse practitioner programs to continue your education and make your own mark on the profession. Every step forward you take is part of a much larger legacy of nurses changing the world.

Sources

Andrea Mosher, CPNP